Not really, I think you cannot totally cut it off from the Universe, can you ?
I'd rather think that it is possible to make them exist in alternate media.
Already, the Net has become a great foyer for meme infection (witness this).
Joshua Lateiner, a student of Dennett has done an interesting short essay on
this.
Logical deductions can be supported by a computer (expert systems, etc...).
It's just a question of having sufficient time and using the following
paradigm :
The way we were made is the way to go to make pseudo-we.
Variation-selection.
Yash.